tutor

导师介绍

王书崎

特聘研究员|博士生导师

1.浙江大学附属第一医院传染病诊治国家重点实验室 2.感染性疾病诊治协同创新中心 3.浙江大学转化医学研究院

电话

邮箱

shuqi@zju.edu.cn

地址

浙江大学华家池校区中心大楼北楼402室

个人简介


教育经历

2009- 2014

美国哈佛大学医学院博士后,研究课题是:Point-of-care   diagnostics for HIV viral load

2005- 2009

英国剑桥大学血液病学博士,研究课题是:Development and assessment of internal   positive controls for HIV-1 nucleic acid based tests for resource-limited   settings

2001-2004

北京协和医科大学、中国医学科学院南京皮研所医学硕士,研究课题是:Cloning and expression of an   immunodominant fragment of glycoprotein G of herpes simplex virus type 2 inE. coli

1995-2000

蚌埠医学院医学学士

 

研究经历

2015 - 至今

浙江大学医学院博导,特聘研究员

2014 - 2015

斯坦福大学医学院助理研究员

主要研究癌症的早期即时诊断。

2010 - 2014

哈佛大学医学院博士后

主要研究Point-of-care diagnostics for HIV viral load

2005 - 2009

英国剑桥大学血液病学博士

主要是研究适合于第三世界的HIV诊断试剂。该研究受到英国Wellcome Trust的大力资助(200万英镑)。博士期间,独立承担了内部质控的研究。该研究贯穿于整个项目的研发。该项目得到法国MSF和美国NIH的资助。目前该产品在美国硅谷Diagnostic for the Real World 进行市场前的进一步定型。

2005 - 2006

英国剑桥大学血液病系任研究助理

参与了乙肝的快速诊断在中国的评估。也同时参与了衣原体和淋球菌快速诊断试剂在菲律宾性工作者中的评估。

2004 - 2005

中国疾病控制与预防中心任研究助理

参与了HIV病毒分离,质粒疫苗,以及RNA干扰为基础的基因治疗。

2001 - 2004

 

中国医学科学院南京皮研所任研究助理

2003-2004 参与国家自然科学基金 “中国性工作者人群中疱疹病毒II 型的流行病学调查(项目资金号. 30170857)

2002-2003 参与美国卫生研究院资助的C-POL项目 “核心人员的干预对HIV和性病预防和治疗的意义。

2002-2003 参与世界卫生组织产前门诊中孕妇性传播疾病的发病率调查

2000 - 2001

安徽省淮北市妇女儿童医院任住院医师。

 

杂志编辑

2012-

Associate editor, Global Journal of Health Science

2012-

Editorial board member International Journal of Biology

2011-

Editorial board member, Medical and Pharmaceutical Journal of Chinese  People’s Liberation Army (Chinese)

2011-

Editorial board member, Clinical Misdiagnosis and Mistherapy (Chinese)

2010-

Editorial board member, Journal of Mechanics in Medicine and Biology

 

承担重大科研项目

2019-2023

无标记循环肿瘤细胞毫米波检测仪研制

2019-2022 

基于数字化器官芯片的肝癌3D体外模型构建及其在抗肿瘤免疫治疗中的研究

2018-2020

艾滋病和病毒性肝炎等重大传染病防治子任务(国家科技重大专项)---HIV新型诊断试剂的开发

2016-2020

新型细胞/组织生物反应器系统仿生构筑研究(十三五国家重点研发计划),2016YFC1101302,子课题负责人,王常勇主持。

   


2012-2016

Novel disposable microchips for HIV-1 viral load, NIH R01 (A1081534).

2012-2013

BWH Biomedical Research Institute Translatable Technologies & Care Innovation Award

2010-2012

Rapid portable platform for multiple-pathogen detection. Department ofDefense (Award No. W81XWH1011050).


获奖情况



协会会员

Infectious Diseases Society of America   (IDSA)

International AIDS Society (IAS)

 

发表论文

1. Lu Siming, Yu Tao, Wang Yimin, Liang Liguo, Chen Yu, Xu Feng and Wang SQ#.  Nanomaterial-based biosensors for measurement of lipids and lipoproteins towards point-of-care of cardiovascular disease. Analyst, 2017,142, 3309-3321#通讯作者)(影响因子:3.885

2.Wang Yimin, Fabio Cuzzucoli, Andres Escobar, Lu Siming, Liang LG, Wang SQ#. Tumor-on-a-chip platforms for assessing nanoparticle-based cancer therapy. Nanotechnology (Accepted)

3. Zhang JW, Zhao X, Liang LG, Li J, Demirci U, Wang SQ#. A decade of progress in liver regenerative medicine. Biomaterials, 2018, 157, 161-176. #通讯作者)(影响因子:8.402

4. Liang LG, Kong MQ, Zhou S, Sheng YF, Wang P, Yu T, Inci F, Kuo WP, Li LJ, Demirci U, andWangSQ#. An integrated double-filtration microfluidic device for isolation, enrichment and quantification of urinary extracellular vesicles for detection of bladder cancer. Scientific Reports. 2017 Apr 24;7:46224. doi: 10.1038/srep46224#通讯作者)(影响因子:4.259

5. Inan H, Wang SQ, Inci F, Baday M, Zangar R, Kesiraju S, Anderson KS, Cunningham BT, Demirci U.Isolation, Detection, and Quantification of Cancer Biomarkers in HPV-Associated Malignancies. Scientific Reports. 2017 Jun 12;7(1):3322. doi: 10.1038/s41598-017-02672-6(影响因子:4.259

6. Wang SQ*#, Chinnasamy T*, Lifson M, Inci F, and Demirci U#. Flexible substrate-based diagnostic devices for point-of-care diagnostics. Trends biotechnol, 2016. doi: 10.1016/j.tibtech.2016.05.009. *共同第一作者)(#通讯作者)(影响因子:11.126

7. Wang SQ, Inci F, De Libero G, Singhal A, and Demirci U. Point-of-care assays for tuberculosis: role of nanotechnology/microfluidics. Biotechnol Adv, 2013. 31(4): p. 438-449.(第一作者)(影响因子:10.597

8. Wang SQ*, Xu F*, and Demirci U. Advances in developing HIV-1 viral load assays for resource-limited settings. Biotechnol Adv, 2010. 28(6): p. 770-781.*共同第一作者)(影响因子:10.597

9. Wang SQ, Esfahani M, Gurkan UA, Inci F, Kuritzkes DR, and Demirci U. Efficient on-chip isolation of HIV subtypes. Lab Chip, 2012. 12(8): p. 1508-1515. (第一作者)(影响因子:6.045

10. Wang SQ, Zhao X, Khimji I, Akbas R, Qiu W, Edwards D, Cramer DW, Ye B, and Demirci U. Integration of cell phone imaging with microchip ELISA to detect ovarian cancer HE4 biomarker in urine at the point-of-care. Lab Chip, 2011. 11(20): p. 3411-3418. (第一作者)(影响因子:6.045

11. Wang SQ, Tasoglu S, Chen PZ, Chen M, Akbas R, Wach S, Ozdemir CI, Gurkan UA, Giguel FF, Kuritzkes DR, and Demirci U. Micro-a-fluidics ELISA for rapid CD4 cell count at the point-of-care. Sci Rep, 2014. 4: p. 3796. DOI: 10.1038/srep03796. (第一作者)(影响因子:4.259

12.Wang SQ, Inci F, Chaunzwa TL, Ramanujam A, Vasudevan A, Subramanian S, Ip ACF, Sridharan B, Gurkan UA, and Demirci U. Portable microfluidic chip for detection of Escherichia coli in produce and blood. Int J Nanomed, 2012. 7: p. 2591-2600. (第一作者)(影响因子:4.300

13. Wang SQ, Sarenac D, Chen MH, Huang SH, Giguel FF, Kuritzkes DR, and Demirci U. Simple filter microchip for rapid separation of plasma and viruses from whole blood. Int J Nanomed, 2012. 7: p. 5019-5028. (第一作者)(影响因子:4.300

14. Wang SQ#, Lifson MA, Inci F, Liang LG, Sheng YF, and Demirci U. Advances in addressing technical challenges of point-of-care diagnostics in resource-limited settings. Expert Rev of Mol Diagn, 2016. 16(4):p.449-459. (第一作者)(# 通讯作者)(影响因子:3.100

15.Wang SQ, Inci F, and Demirci U. Detection of Peritonitis in Patients on Peritoneal Dialysis at Home. IEEE Pulse, 2015, http://pulse.embs.org/september-2015/detection-of-peritonitis-in-patients-on-peritoneal-dialysis-at-home/.(第一作者)(影响因子:0.500

16.Wang SQ, Inci F, and Demirci U. Assisted Reproductive Microchip Technologies to Improve Infertility. IEEE Pulse, 2015, http://pulse.embs.org/january-2015/assisted-reproductive- technologies-improve-infertility/.(第一作者)(影响因子:0.500

17.Mani V*, Wang SQ*, Inci F*, De Libero G, Singhal A, and Demirci U. Emerging technologies for monitoring drug-resistant tuberculosis at the point-of-care. Adv Drug Deliv Rev, 2014. 78: p. 105-117.*共同第一作者)(影响因子:11.764

18. Hu J*, Wang SQ*, Wang L, Li F, Pingguan-Murphy B, Lu TJ, and Xu F. Advances in paper-based point-of-care diagnostics. Biosens Bioelectron, 2014. 54: p. 585-597.*共同第一作者)(影响因子:7.780

19. Han YL*, Wang SQ*, Zhang XH, Li YH, Huang GY, Qi H, Pingguan-Murphy B, Li YH, Lu TJ, and Xu F. Engineering physical microenvironment for stem cell based regenerative medicine. Drug Discov Today, 2014. 19(6): p. 763-773.*共同第一作者)(影响因子:6.369

20. Wei HL*, Wang SQ*, Xu F, Xu LF, Zheng JR, and Chen Y. Evaluation of a 13-hexyl-berberine hydrochloride topical gel formulation. Drug Dev Ind Pharm, 2013. 39(4): p. 534-539.*共同第一作者)(影响因子:2.295

21.Wei HL*, Wang SQ*, Xu F, Xu LF, Zheng JR, and Chen Y. Topical bioequivalence of acyclovir creams using dermal microdialysis in pigs: a new model to evaluate bioequivalence for topical formulations. Drug Dev Ind Pharm, 2012. 38(7): p. 785-791.*共同第一作者)(影响因子:2.295

22. Zhang W*, Wang SQ*, Lin M, Han Y, Zhao G, Lu TJ, and Xu F. Advances in experimental approaches for investigating cell aggregate mechanics. Acta Mech Solida Sin, 2012. 25(5): p. 473-482.*共同第一作者)(影响因子:0.736

23. Wei HL, Hu J, Wang L, Xu F#, and Wang SQ#. Rapid gene splicing and multi-sited mutagenesis by one-step overlap extension polymerase chain reaction. Anal Biochem, 2012. 429(1): p. 76-78.#通讯作者)(影响因子:2.334

24.Yang GH, Wang SQ#, Wei HL, Ping J, Liu J, Xu LM, and Zhang WW. Patch oligodeoxynucleotide synthesis (POS): a novel method for synthesis of long DNA sequences and full-length genes. Biotechnol Lett, 2012. 34(4): p. 721-728.#通讯作者)(影响因子:1.730

25.Shafiee H, Wang SQ, Inci F, Toy M, Henrich TJ, Kuritzkes DR, and Demirci U. Emerging technologies for point-of-care management of HIV infection. Annu Rev Med, 2015. 66: p. 387-405.(影响因子:13.609

26.Luo ZY, Wang SQ, He L, Xu F, and Bai BF. Inertia-dependent dynamics of three-dimensional vesicles and red blood cells in shear flow. Soft Matter, 2013. 9(40): p. 9651-9660.(影响因子:3.889

27. Luo ZY, Wang SQ, He L, Lu TJ, Xu F, and Bai BF. Front tracking simulation of cell detachment dynamic mechanism in microfluidics. Chem Eng Sci, 2013. 97: p. 394-405.(影响因子:2.895

28. Tasoglu S, Gurkan UA, Wang SQ, and Demirci U. Manipulating biological agents and cells in micro-scale volumes for applications in medicine. Chem Soc Rev, 2013. 42(13): p. 5788-5808.(影响因子:38.618

29. Inci F, Tokel O, Wang SQ, Gurkan UA, Tasoglu S, Kuritzkes DR, and Demirci U. Nano-plasmonic quantitative detection of intact viruses from unprocessed whole blood. ACS Nano, 2013. 7(6): p. 4733-4745.(影响因子:13.942

30. Yildiz UH, Inci F, Wang SQ, Toy M, Tekin HC, Javaid A, Lau DTY, and Demirci U. Recent advances in micro/nanotechnologies for global control of hepatitis B infection. Biotechnol Adv, 2015. 33(1): p. 178-190.(影响因子:10.597

31. Lin M, Zhao Y, Wang SQ, Liu M, Duan ZF, Chen YM, Li F, Xu F, and Lu TJ. Recent advances in synthesis and surface modification of lanthanide-doped upconversion nanoparticles for biomedical applications. Biotechnol Adv, 2012. 30(6): p. 1551-1561.(影响因子:10.597

32.Choi JR, Hu J, Wang SQ, Yang H, Wan Abs WA, Pingguan-Murphy B, and Xu F. Paper-based Point-of-Care Testing for Diagnosis of Dengue Infections.Crit Rev Biotechnol, 2016.p.1-12(影响因子:6.542

33. Choi JR, Tang RH, Wang SQ, Abas WAW, Pingguan-Murphy B, and Xu F.Paper-based sample-to-answer molecular diagnostic platform for point-of-care diagnostics. Biosens Bioelectron, 2015. 74: p. 427-439.(影响因子:7.780

34. Hu J, Choi JR, Wang SQ, Gong Y, Feng SS, Pingguan-Murphy B, Lu TJ, and Xu F.Multiple test zones for improved detection performance in lateral flow assays.Sensor Actuat B-Che, 2016.DOI: 10.1016/j.snb.2016.12.008. (影响因子:5.401

35. Huang GY, Wang L, Wang SQ, Han YL, Wu JH, Zhang QC, Xu F, and Lu TJ. Engineering three-dimensional cell mechanical microenvironment with hydrogels. Biofabrication, 2012. 4(4): p. 042001. DOI: 10.1088/1758-5082/4/4/042001.(影响因子:5.240

36.Xu F, Wu JH, Wang SQ, Durmus NG, Gurkan UA, and Demirci U. Microengineering methods for cell-based microarrays and high-throughput drug-screening applications. Biofabrication, 2011. 3(3): p. 034101. DOI: 10.1088/1758-5082/3/3/034101(影响因子:5.240

37. Sha BY, Gao W, Wang SQ, Xu F, and Lu TJ. Cytotoxicity of titanium dioxide nanoparticles differs in four liver cells from human and rat. Compos Part B-Eng, 2011. 42(8): p. 2136-2144.(影响因子:4.727

38.Zhou LH, Huang GY, Wang SQ, Wu JH, Lee WG, Chen YM, Xu F, and Lu TJ. Advances in cell-based biosensors using three-dimensional cell-encapsulating hydrogels. Biotech J, 2011. 6(12): p. 1466-1476.(影响因子:2.599

39. Sha BY, Gao W, Wang SQ, Li W, Liang X, Xu F, and Lu TJ. Nano-titanium dioxide induced cardiac injury in rat under oxidative stress. Food Chem Toxicol, 2013. 58: p. 280-288.(影响因子:3.778

40. Luo ZY, He L, Wang SQ, Tasoglu S, Xu F, Demirci U, and Bai BF. Two-dimensional numerical study of flow dynamics of a nucleated cell tethered under shear flow. Chem Eng Sci, 2014. 119: p. 236-244.(影响因子:2.895

41. Sha BY, Gao W, Wang SQ, Gou XC, Li W, Liang X, Qu ZG, Xu F, and Lu TJ. Oxidative stress increased hepatotoxicity induced by nano-titanium dioxide in BRL-3A cells and Sprague-Dawley rats. J Appl Toxicol, 2014. 34(4): p. 345-356.(影响因子:3.159

42. Xu F, Sridharan B, Wang SQ, Gurkan UA, Syverud B, and Demirci U. Embryonic stem cell bioprinting for uniform and controlled size embryoid body formation. Biomicrofluidics, 2011. 5(2): p. 22207. DOI: 10.1063/1.3580752(影响因子:2.535

43. Bai BF, Luo ZY, Wang SQ, He L, Lu TJ, and Xu F. Inertia effect on deformation of viscoelastic capsules in microscale flows. Microfluid Nanofluid, 2013. 14(5): p. 817-829.(影响因子:2.344

44. Lin M, Zhai X, Wang SQ, Wang ZJ, Xu F, and Lu TJ. Influences of supra-physiological temperatures on microstructure and mechanical properties of skin tissue. Med Eng Phys, 2012. 34(8): p. 1149-1156.(影响因子:1.819

45. Mark A Lifsona, Mehmet Ozgun Ozen, Fatih Incia, Wang SQ, Hakan Inana, Murat Baday, Timothy J. Henrich, and Demirci U. Advances in biosensing strategies for HIV-1 detection, diagnosis, and therapeutic monitoring. Adv Drug Deliver Rev, 2016. doi: 10.1016/j.addr.2016.05.018(影响因子:11.764

46. Shafiee H, Jahangir M, Inci F, Wang SQ, Willenbrecht RBM, Giguel FF, Tsibris AMN, Kuritzkes DR, and Demirci U. Acute on-chip HIV detection through label-free electrical sensing of viral nano-lysate. Small, 2013. 9(15): p. 2553-2563, 2478.(影响因子:8.643

47. Xu XY, Akay A, Wei HL, Wang SQ, Pingguan-Murphy B, Erlandsson BE, Li XJ, Lee WG, Hu J, Wang L, and Xu F. Advances in Smartphone-Based Point-of-Care Diagnostics. P IEEE, 2015. 103(2): p. 236-247.(影响因子:9.237

48. Wang L, Huang G, Sha B, Wang SQ, Han YL, Wu J, Li Y, Du Y, Lu TJ, and Xu F. Engineering three-dimensional cardiac microtissues for potential drug screening applications. Curr Med Chem, 2014. 21(22): p. 2497-2509.(影响因子:3.249

49. Xu F, Sridharan B, Durmus NG, Wang SQ, Yavuz AS, Gurkan UA, and Demirci U. Living bacterial sacrificial porogens to engineer decellularized porous scaffolds. PLoS One, 2011. 6(4): p. e19344. DOI: 10.1371/journal.pone.0019344(影响因子:2.806

50. Sha B, Gao W, Han Y, Wang SQ, Wu J, Xu F, and Lu TJ. Potential application of titanium dioxide nanoparticles in the prevention of osteosarcoma and chondrosarcoma recurrence. J Nanosci Nanotechnol, 2013. 13(2): p. 1208-1211.(影响因子:1.483

51. Tasoglu S, Tekin HC, Inci F, Knowlton S, Wang SQ, Wang-Johanning F, Johanning G, Colevas D, and Demirci U. Advances in Nanotechnology and Microfluidics for Human Papillomavirus Diagnostics. P IEEE, 2015. 103(2): p. 161-178. (影响因子:9.237

52.Han YL, Wang Wq, Hu J, Huang GY, Wang SQ, Lee WG, Lu TJ, and Xu F. Benchtop fabrication of three-dimensional reconfigurable microfluidic devices from paper-polymer composite. Lab Chip, 2013. 13(24): p. 4745-4749. (影响因子:6.045

53. Gurkan UA, Moon S, Geckil H, Xu F, Wang SQ, Lu TJ, and Demirci U. Miniaturized lensless imaging systems for cell and microorganism visualization in point-of-care testing.Biotech J, 2011. 6(2): p. 138-149. (影响因子:2.599

54. Qi H, Huang GY, Han YL, Lin W, Li XJ, Wang SQ, Lu TJ, and Xu F. In vitro spatially organizing the differentiation in individual multicellular stem cell aggregates. Crit Rev Biotechnol, 2016. 36(1): p. 20-31. (影响因子:6.542

55. Inci F, Filippini C, Baday M, Ozen MO, Calamak S, Durmus NG, Wang SQ, Hanhauser E, Hobbs KS, Juillard F, Kuang PP, Vetter ML, Carocci M, Yamamoto HS, Takagi Y, Yildiz UH, Akin D, Wesemann DR, Singhal A, Yang PL, Nibert ML, Fichorova RN, Lau DT, Henrich TJ, Kaye KM, Schachter SC, Kuritzkes DR, Steinmetz LM, Gambhir SS, Davis RW, and Demirci U. Multitarget, quantitative nanoplasmonic electrical field-enhanced resonating device (NE2RD) for diagnostics. Proc Natl Acad Sci USA, 2015. 112(32): p. E4354-4363. (影响因子:9.661

56. Mani V, Paleja B, Larbi K, Kumar P, Tay JA, Siew JY, Inci F, Wang SQ, Chee C, Wang YT, Demirci U, Libero DG, and Singhal A. Microchip-based ultrafast serodiagnostic assay for tuberculosis. Scientific Reports,2016. 24(6): p. 35845. (影响因子:4.259

57. Liu AY, Zang WJ, Yuan LL, Chai YL, and Wang SQ#. Latent Syphilis among Inpatients in an Urban Area of China. Global Journal of Health Science, 2015. 7(3): p. 249-253. #通讯作者)

58. Yucha RW, Hobbs KS, Hanhauser E, Hogan LE, Nieves W, Ozen MO, Inci F, York V, Gibson EA, Thanh C, Shafiee H, EI Assal R, Kiselinova M, Robies YP, Bae H, Leadabrand KS, Wang SQ, Deeks SG, Kuritzkes DR, Demirci U*, Henrich TJ*. High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay. EBioMedicine, 20, 217-229. 2017.

59. Yew T, Chen XS, Feng SS, Yang Q, Wang SQ, Wee WH, Pingguan-Murphy B, Lu TJ, Xu F.Paper-based capacitive sensors for identification and quantification of chemicals at the point of care. Talanta, 165, 419. 2017.(浙江大学非第一通讯单位)(IF4.162

60. Zhao GX, Zhang YJ, Zhang L, Ye ZG, Ren W, Xu F, WangSQ, Liu M, Zhang XH. 3D Conformal Modification of Electrospun Silk Nanofibers with Nanoscaled ZnO Deposition for Enhanced Photocatalytic Activity. Acs Biomaterials science & engineering, 2017, 3 (11): 2900-2906. (IF 4.432)

61. Jie Hu, Jane RuChoi, Wang SQ, Yan Gong, Shangsheng Feng, Belinda Pingguan-Murphy, TianJian Lu, FengXu. Multiple test zones for improved detection performance in lateral flow assays. Sensors & Actuators B Chemical, 2017, 243 :484-488. (IF 5.667)

62. Yucha RW, Hobbs KS, Hanhauser E, Hogan LE, Nieves W, Ozen MO, Inci F, York V, Gibson EA, Thanh C, Shafiee H, EI Assal R, Kiselinova M, Robies YP, Bae H, Leadabrand KS, Wang SQ, Deeks SG, Kuritzkes DR, Demirci U, Henrich TJ. High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay. EBioMedicine, 2017, 20 (C) :217-229. (IF 6.183)

63.L Liang, Y Wang, S Lu, M Kong,  L Yong, F Cuzzucoli, P Wang, SQ Wang. Microchips for detection of exfoliated tumor cells in urine for identification of bladder cancer, Analytica Chimica Acta, 2018, Accepted. (IF 5.123)

64.Siming Lu, Fabio Cuzzucoli, Jing Jiang, Li-guo Liang, Yiming Wang, Mengqi Kong, Xin Zhao, Wenguo Cui, Jun Li, Wang, SQ, Development of a biomimetic liver tumor-on-a-chip model based on decellularized liver matrix for toxicity testing, Lab Chip, 2018, Accepted. (IF 5.995)

65. Wang YCuzzucoli FEscobar ALu SLiang L,Wang, SQ. Tumor-on-a-chip platforms for assessing nanoparticle-based cancer therapy, Nanotechnology. 2018,17;29(33):332001.DOI: 10.1088/1361-6528/aac7a4. (IF 3.404)

66. Y.F. Ma, M. Lin, G.Y. Huang, Y.H. Li, Wang, SQ, G.Q. Bai, T.J. Lu, F. Xu, Three-Dimensional Spatiotemporal Mechanical Microenvironment: A Hydrogel-Based Platform for Guiding Stem Cell Fate, Advanced Materials, 2018, 1-27, DOI: 10.1002/adma.201705911. (IF 21.95)

 

书籍章节

1. Wang SQ, Akbas R, and Demirci U. Microchip ELISA Coupled with Cell Phone to Detect Ovarian Cancer HE4 Biomarker in Urine. Mobile Health (mHealth) Technologies. (Edited by Rasooly A and Herold KE). Methods in Molecular Biology, Humana Press, p. 111-121, 2015.

2. Chen P *, Wang SQ *, Inci F, Güven S, Tasoglu S, and Demirci U. Cell Encapsulating Hydrogels for Biosensing. (Edited by Khademhosseini A, and Demirci U). World Scientific Publishing Company. 2014 (*共同第一作者).

3. Li BQ, Meng F, Jin L, Wang L, Wang SQ, Wei D, Jia D, and Zhou Y. Chitosan Hemostatic Dressing. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. (Edit by Mishra M). CRC Press of Taylor and Francis Group, 2014

4. Wang SQ, Esfehani M, Sarenac D, Cheung B, Vasudevan A, Xu F, and Demirci U. Applications of Quantum Dots for Fluorescence Imaging in Biomedical Research. Microfluidic Technologies for Human Health (Edited by Demirci U, Langer B, Khademhosseini A, Blander J). p. 451-470, 2013.

5. Luo ZY, Wang SQ, Demirci U, Lu TJ, Xu F, and Bai BF. Antibody Based Blood Bioparticles Capture and Separation using Microfluidics for Global Health. Microfluidic Technologies for Human Health. World Scientific Publishing, p. 417-450, 2012.

6.Han YL, Zhou LH, Wang SQ, Wu JH, Duan ZF, Lu TJ, and Xu F. Advances in Chondrosarcoma Treatment: Engineering in vitro Three-Dimensional Models. Nova Science Publishers, p. 85-106, 2011.

7. Wang SQ, Xu F, Ip A, Keles HO, and Demirci U. Emerging microscale technologies for global health: CD4+ counts. Biotechnology II: Global Prospects. (Edited by Reisner DE). CRC Press, p. 115-127, 2010.

8. Wang SQ, Xu F, Ip A, Mrudula S, Zhao XH, Akay A, and Demirci U. Surface chemistry for cell capture in microfluidic systems. Systems and Nanotechnology: MEMs, Photonic and Biological Interfaces (Edited by Iniewski K). Taylor & Francis, p. 551-562, 2010.

9.Wang SQ, Doshi P, Wei HL, Segan R, Lu TJ, and Xu F. Global health: dengue/dengue hemorrhagic fever. Distributed Diagnosis and Home in Healthcare (D2H2) - Vol.3 (Edited by Ng EYK, Acharya R, and Tamura T). American Scientific Publishers, 2010.

10. Wang SQ, Wei HL, Zhao X, Yuan A, Lu TJ, Hu YQ, Wu JH, and Xu F. Rapid tests for the point of care: a case of HIV. Distributed Diagnosis and Home in Healthcare (D2H2) - Vol.3 (Edited by Ng EYK, Acharya R, and Tamura T). American Scientific Publishers, 2010.

11. Liang LG, Sheng YF, Zhou S, Inci F, Li LJ, Demirci U, Wang SQ. An integrated double-filtration microfluidic device for detection of extracellular vesicles (EVs) from urine for bladder cancer diagnosis. Methods in Molecular Biology, Humana Press, In press, 2016.

专利申请

1. Wang SQ, Demirci U, Ye B, and Akbas R. System and method for integration of mobile device imaging with microchip ELISA. Publication No.: WO2013010178A1.

2. Wang SQ, Wei HL, and Xu F. Rapid bidirectional multiple gene mutation method. Publication No.: CN102690807 A.

3. Xu F, Hu J, Wang SQ, Tu TJ, and Wang L. A novel method to increase the signal on dipsticks. Publication No.: CN 103267854 A

4.一种尿液外泌体ELISA的检测方法及其应用. 发明人:梁利国,盛叶峰,孔梦奇,王书崎。申请时间2016.06.06,申请中,已受理。申请号:201610387088.6

5.一种尿液外泌体分离、富集及检测的集成检测方法及检测芯片。发明人:梁利国,孔梦奇,盛叶峰,王书崎。申请时间2016.06.07,申请中,已受理。申请号:201620531552.X

6.一种用于外泌体分离、富集和检测的微流体芯片(实用新型专利)。发明人:梁利国,王书崎。申请时间2016.06.07,申请中,已受理。申请号:201610386872.5

7.一种进行核酸扩增检测的装置及方法。发明人:孔梦奇,盛叶峰,梁利国,余涛,王书崎。申请时间2017.04.17,申请中,已受理。申请号:201710248640.8

8.一种进行核酸扩增检测的装置(实用新型专利)。发明人:孔梦奇,余涛,盛叶峰,王书崎。申请时间2017.04.17,申请中,已受理。申请号:201720399048.3

9. 一种数字化微阵列器官芯片及其应用(实用新型专利)。发明人:王书崎,王怡敏,陆思铭,梁利国。申请中,已受理。申请号:201810298289.8

10. 一种数字化微阵列器官芯片及其应用。发明人:王书崎,王怡敏,陆思铭,梁利国。申请中,已受理。申请号:201820475403.5

11. 一种快速检测淋球菌最小抑菌浓度的装置(实用新型专利)。发明人:王书崎,王怡敏,梁利国。申请中,已受理。申请号:201820968947.5

12. 一种快速检测淋球菌最小抑菌浓度的装置、制备及检测方法。发明人:王书崎,王怡敏,梁利国。申请中,已受理。申请号:201810651777.2

13. 一种脱细胞支架溶液-GelMA水凝胶复合材料及制备方法。发明人:王书崎,陆思铭,梁利国,王怡敏。申请中,已受理。申请号:2018110293996.7

 

会议文章

1.Liang LG, Sheng YF, Zhou S, Kong MQ, Yu T, Gong RZ, Inci F, Demirci U, and Wang SQ#.An integrated double-filtration device for detection of exosomes from urine for bladder cancer diagnosis. TERMIS-AP Meeting, Taibei, Tai Wan, 2016.

2. Wang SQ, Zhao X, Khimji I, Edwards D, Qiu W, Cramer, DW, Ye B, and Demirci U. Integration of Cell Phone Imaging with Microchip ELISA to Detect Ovarian Cancer HE4 Biomarker in Urine at the Point-of-Care. 2012 USNC-URSI National Radio Science Meeting: Paper #1478, Boulder. Colorado, 2012.

3. Wang SQ, Zhao X, Khimji I, Edwards D, Qiu W, Cramer, DW, Ye B, and Demirci U. Integration of Cell Phone Imaging with Microchip ELISA to Detect Ovarian Cancer HE4 Biomarker in Urine at the Point-of-Care. Future diagnostics: point-of-care diagnostics. University of California Irvine, 2012.

4. Wang SQ, Moon, SJ, Gurkan UA, Blander J, Eligius L, Fawzi W, Aboud, S, Mugusi, F, Kuritzkes D, and Demirci U. Microchip based antiretroviral treatment (ART) monitoring of HIV at the point-of-care (POC). ATACCC 2011 conference. Fort Lauderdale, FL, USA, 2011.

5. Wang SQ, Sarenac D, Chen M, Huang SH, Giguel FF, Kuritzkes DR, and Demirci U. Efficient Capture and Detection of HIV Subtypes by Oriented Antibody Immobilization in a Microchip for Enhanced HIV Viral Load Detection Applications. MRS Fall, Boston, December 2011.

6. Wang SQ, Esfahani M, Gurkan, UA, Kuritzkes DR, and Demirci U. Rapid, Label-Free Sample Preparation Microchip for Sorting Blood Components at the POC. MRS Fall, Boston, December 2011.

7. Wang SQ, Esfahani M, Gurkan UA, Kuritzkes D, and Demirci U. Protein-G based surface chemistry for HIV detection on-chip. Biomedical Engineering Society Annual Conference, Hartford, CT, USA, 2011.

8. Wang SQ, Esfahani M, Cheung B, Gurkan UA, Kuritzkes D, and Demirci U. Surface chemistry for detection of HIV in a microfluidic device. American Association for Clinical Chemistry 43rd Oak Ridge Conference: Emerging Technologies for 21st Century Clinical Diagnostics, April 14-15, 2011.

9. Wang SQ, Esfahani M, Gurkan UA, Kuritzkes D, and Demirci U. Protein-G based antibody immobilization for HIV detection on-chip. Massachusetts Life Sciences Innovation Day, Boston, MA, USA, 2011.

10. Wang SQ, Moon SJ, and Demirci U. A microchip platform technology for global health. Unite for sight, New Haven, CT, USA, 2011.

11. Wang SQ, Ip A, Cheung WH, Xu F, Somu M, Manzur T, Zhao X, Karakasoglu I, Akay A, and Demirci U. Validation of Escherichia coli capture on portable microchips for point-of-care applications. Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Security and Homeland Defense. SPIE Defense, Security, and Sensing Orlando, FL, USA, 2011.

12. Wang SQ, Zhao X, Khimji I, Edwards D, Qiu W, Cramer D, Ye B, and Demirci U. Cell Phone Detects Cancer from Urine. URSI National Meeting Special Session on Telemetry for Monitoring and Biosensing Boulder, CO, USA, 2011.

13. Moon SJ, Wang SQ, Gurkan UA, Blander J, Eligius L, Fawzi W, Aboud S, Mugusi F, Kuritzkes D, and Demirci U. A Point-of-Care Microchip Platform for HIV-1 Monitoring and Diagnostics. United States African Command (AFRICOM), Germany, 2011.

14. Xu F, Sridharan B, Wang SQ, Gurkan UA, Syverud B, and Demirci U. Stem cell printing for controlled-size embryoid body formation. 2011 MRS Spring Meeting, Moscone West and San Francisco Marriott San Francisco, CA, USA, April 25-29, 2011.

15. Xu F, Sridharan B, Yavuz AS, Wang SQ, Durmus NG, Gurkan UA, and Demirci U. Fabrication of Porous Hydrogels with Embedded Microchannels Using Living Sacrificial Porogens. MRS Fall, Boston, December 2011.

16. Wang SQ, Moon SJ, and Demirci U. Microchips enable HIV antiretroviral treatment monitoring at the point-of-care (POC). NIAID US-JAPAN, 24th Joint Meeting of the AIDS Panels, Singapore, December 2010.

17. Wang SQ, Moon SJ, and Demirci U. A Point-of-Care (POC) Platform for HIV-1 Diagnostics. NIAID US-JAPAN 14th International Conference on Emerging Infectious Diseases (EID) in the Pacific Rim, Penang, Malaysia, October 2010.

18. Wang SQ, Ip A, Xu F, Giguel FF, Moon S, Akay A, Kuritzkes DR, and Demirci U. Development of a microfluidic system for measuring HIV-1 viral load. SPIE Proceedings, 2010; 7666-53.

19. Wang SQ, Moon SJ, Kuritzkes D, and Demirci U. Microfluidic Devices for HIV Point-of-Care Monitoring. Massachusetts Life Sciences Innovation Day, Boston, MA, USA. 2010.

20. Xu F, Yavuz AS, Sridharan B, Wang SQ, and Demirci U. Bacterial printing for fabricating microfluidic hydrogels. 2010 International Conference of Biofabrication, Philadelphia, USA, October 4-6, 2010.

21. Lee H, Wang SQ, Dineva M, Ritchie A, Wei HL, and Magbanua F. Rapid Tests for HIV monitoring in resource-limited settings. 6th IABs symposium on advances in transfusion safety, Cambridge, UK, July 2009.

22. Lee H, Wang SQ, Dineva M, Ritchie A, Magbanua F, and Wei HL. Disposable micro-cartridge for HIV monitoring in resource-limited settings. 18th International Society for STD research in conjunction with BASSH, London, July 2009.

23.Wang SQ, Yin YP, Lai WH, Jiang MJ, Chen Q, and Chen XS. Cloning and expression of an immunodominant fragment of glycoprotein G of HSV-2 using directional TOPO vector in E. coli. IX International Congress of Dermatology in Beijing, China, May, 2004.

中文文章

1. Wei HL, Jiang FX, Xu F#, and Wang SQ#. Application of immunographic assays for point-of-care diagnosis of sexually transmitted infections. Medical and Pharmaceutical Journal of Chinese People’s Liberation Army, 2012. 24(4):P. 1-4. (#通讯作者)

2. Hu J, Wang L, Wei HL, Wang SQ#, and Xu F#. Progression in point-of-care testing for tuberculosis. Medical and Pharmaceutical Journal of Chinese People’s Liberation Army, 2012. 24(8):P. 4-9 (#通讯作者)

3. Wang SQ, Yin YP, Lai WH, Jiang MJ, Chen Q, and Chen XS. Cloning and expression of an immunodominant fragment of glycoprotein G of HSV-2 using directional TOPO vector in E. coli. Chinese Journal of Dermatology, 2005. 38(05):p. 288-290.

4. Jiang MJ, Wang SQ, Yu Y, Yin YP, and Sun JF. DNA sequencing of HPV cp6108 Gene - a new variant. Chinese Journal of Dermatology, 2005. 38(09):p. 543-545.

5. Jiang MJ, Wang SQ, Gong XD, Chen Q, Yin YP, and Sun JF. Genotyping of Human Papillomavirus in Condyloma Acuminata. Chinese Journal of Dermatology, 2005. 38(05): p. 262-264.

6. Tucker J, Wang SQ, and Wei HL, Chen Q, and Chen XS. Collaborating against AIDS: a urban Chinese case study of world AIDS Day awareness. Chinese Journal of Sexually Transmitted Infections, 2004. 4(02): p. 115-118.

7. Wei HL, Wang SQ, and Gong X. Advance in HPV Vaccine. International Progress in Medical Sciences, 2004. p. 129-133.

8. Liu AY, Sun JF, Yin YP, Chen XS, and Wang SQ. Detection of pathogens causing genital ulcer diseases using gene chips. Chinese Journal of Dermatology, 2004. 37(05): p. 265-267.

9. Liu AY, Sun JF, Yin YP, Chen XS, Wang SQ. and Xu M, Detection of treponema pallidum by polymerase chain reaction. Chinese Journal of Clinical Dermatology, 2004. 33(07): p. 413-415.

10.Xu M, Yin YP, Yu YH, Liu AY, and Wang SQ. Selection of primers and optimization of PCR for trichomonas vaginalis. Chinese Journal of Dermatology, 2004. 37(10): p. 603-605.

11. Wang SQ, and Yin YP. Progress on the development of genital herpes vaccine. Foreign Medical Sciences Section of Dermatology and Venereology, 2003. 29(03): p. 189-192.



 



 








研究方向

数字化器官芯片,癌症早期即时诊断与组织器官药物筛选模型