研究生教育

学习工作经历

2019.6-                 浙江大学药学院，特聘研究员

2018.5-2019.5      苏州诺华制药科技有限公司，Senior Scientist

2017.8-2018.5      新加坡国立大学化学系，博士后

2016.5-2016.11    新加坡国立大学化学系，研究助理

2012.8-2016.9      新加坡国立大学，有机化学，博士

2008.9-2012.6      浙江大学，药学，学士

Independent

1. Yulong Kong, Kui Zeng, Ying Zhang, Jinning Shao, Jiaqi Yan, Jia-Yu Liao, Wenchao Wang, Xiaoyang Dai, Qinjie Weng, Shao Q. Yao, Su Zeng,* and Linghui Qian.* In vivo targeted delivery of antibodies into cancer cells with pH-responsive cell-penetrating poly(disulfide)s, Chem. Commun. 2022, 58, 1314-1317. 
   

2. Linghui Qian,# Ling-Fei Tao,# Wen-Tao Wang, Ehtesham Jameel, Zhang-Hong Luo, Tao Zhang, Yu Zhao, and Jia-Yu Liao.* Catalytic Atroposelective Dynamic Kinetic Resolution of Biaryl Lactones with Activated Isocyanides. Org. Lett. 2021, 23, 5086-5091. (# These authors contributed equally to this work.)

3. Yuchen Zhu (UG), Jia-Yu Liao,* and Linghui Qian.* Isocyanides: Promising Species in Bioorthogonal Labeling of Biomolecules. Front. Chem. 2021, 9, 670751. (UG: 本科生)

Previous

1. Caizhi Wu, Jiayu Liao, and Shaozhong Ge.* Cobalt-Catalyzed Enantioselective Hydroboration/Cyclization of 1,7-Enynes: Asymmetric Synthesis of Chiral Quinolinones Containing Quaternary Stereogenic Centers. Angew. Chem. Int. Ed. 2019, 58, 8882-8886. Selected as Hot Paper.

2. Germaine Pui Yann Kok,# Pan-Lin Shao,#* Jia-Yu Liao, Siti Nur Fairuz Bte Sheikh Ismail, Weijun Yao, Yixin Lu,* and Yu Zhao.* Divergent, Enantioselective Synthesis of Pyrroles, 3H-Pyrroles and Bicyclic Imidazolines by Ag- or P-Catalyzed [3+2] Cycloaddition of Allenoates with Activated Isocyanides. Chem. Eur. J. 2018, 24, 10513-10520. (# These authors contributed equally to this work.) Selected as Hot Paper.

3. Jia-Yu Liao, Qijian Ni, and Yu Zhao.* Catalyst-Enabled Scaffold Diversity: Highly Chemo- and Stereoselective Synthesis of Tricyclic Ketals and Triarylmethanes. Org. Lett. 2017, 19, 4074-4077. Highlighted in Synfacts 2017, 13, 1053.

4. Jia-Yu Liao, Wei Jie Yap, Ji'En Wu, Ming Wah Wong,* and Yu Zhao.* Three-Component Reactions of Isocyanoacetates, Amines and 3-Formylchromones Initiated by an Unexpected aza-Michael Addition. Chem. Commun. 2017, 53, 9067-9070.

5. Jia-Yu Liao,# Pan-Lin Shao,# and Yu Zhao.* Catalytic Divergent Synthesis of 3H or 1H Pyrroles by [3+2] Cyclization of Allenoates with Activated Isocyanides. J. Am. Chem. Soc. 2015, 137, 628-631. (# These authors contributed equally to this work.)

6. Pan-Lin Shao, Jia-Yu Liao, Yee Ann Ho, and Yu Zhao.* Highly Diastereo- and Enantioselective Silver-Catalyzed Double [3+2] Cyclization of α-Imino Esters with Isocyanoacetate. Angew. Chem. Int. Ed. 2014, 53, 5435-5439. Highlighted in Synfacts 2014, 10, 0846.

7. Linghui Qian, Jiayu Liao, Yani Li, Xiaofan Mo, Li Ma, and Tongwei Yao.* Comparison of Three Methods on Assay for Vitamin A: UV, NP-HPLC and RP-HPLC. Experimental Technology and Management 2012, 5, 43-48.