研究生教育

 张钧，医学博士，博士生导师，主任检验医师，浙江大学医学院附属邵逸夫医院检验科主任；浙江省医学会检验医学会候任主任委员；中国医师协会检验医师分会青年委员会副主任委员,中华医学会检验医学分会青年委员; 浙江省医师协会检验医师分会总干事；北京医学奖励基金会检验医学专委会副主任委员;中国医药教育协会检验医学专业委员会委员;中国中西医结合学会检验专业分会委员;中国研究型医院生物标志物委员会常务委员； 

研究与成果：主要研究方向：感染与肿瘤；肿瘤免疫；个体化检验诊断;生物标志物的研究及临床应用；转化医学。作为主要研究者参与或主持了国家自然基金课题4项,浙江省重大专项2项,自然基金3项,省厅级课题多项,近5年发表学术论文60余篇,其中SCI40余篇。参编教材2部,获浙江省政府科技成果三等奖2项、浙江省卫生厅科技成果二等奖1项。

代表性论文：

 [1]Zeng J, Li G, Xia Y, Wang F, Wang Y, Xu S, Zhou Y, Liu X, Xie X, Zhang J (2020) miR-204/COX5A axis contributes to invasion and chemotherapy resistance in estrogen receptor-positive breast cancers. Cancer letters 492:185-196

[2]Yuan S, Xia Y, Shen L, Ye L, Li L, Chen L, Xie X, Lou H, Zhang J (2020) Development of nomograms to predict therapeutic response and prognosis of non-small cell lung cancer patients treated with anti-PD-1 antibody. Cancer Immunology Immunotherapy. doi: 10.1007/s00262-020-02710-9

[3]Yu H, Zhou X, Wang Y, Huang X, Yang J, Zeng J, Li G, Xie X, Zhang J (2020) Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells. Cancer cell international 20 (1): 191

 [4]Yang T, Pan L, Wu N, Wang L, Liu Z, Kong Y, Ruan Z, Xie X, Zhang J (2020) Antimicrobial Resistance in Clinical Ureaplasma spp. and Mycoplasma hominis and Structural Mechanisms Underlying Quinolone Resistance. Antimicrobial agents and chemotherapy 64 (6): e02560-19

[5]Yang T, Li X, Zhang Y, Kong Y, Yu H, Ruan Z, Xie X, Zhang J (2020) Comparative genomics of three clinical Ureaplasma species: analysis of their core genomes and multiple-banded antigen locus. Future microbiology 15 (1):49-61

 [6]Liu F, Xu A, Zhang Y, Xuan W, Yan T, Pan K, Yu W, Zhang J (2020) Patients of COVID-19 may benefit from sustained Lopinavir-combined regimen and the increase of Eosinophil may predict the outcome of COVID-19 progression. International Journal of Infectious Diseases 95:183-191

 [7]Jin H, Fu X, Cao X, Sun M, Wang X, Zhong Y, Yang S, Qi C, Peng B, He X, He F, Jiang Y, Gao H, Li S, Huang Z, Li Q, Fang F, Zhang J (2020) Developing and Preliminary Validating an Automatic Cell Classification System for Bone Marrow Smears: a Pilot Study. Journal of medical systems 44 (10): 184

 [8]Wang Y, Zeng J, Wu W, Xie S, Yu H, Li G, Zhu T, Li F, Lu J, Wang GY, Xie X, Zhang J (2019) Nicotinamide N-methyltransferase enhances chemoresistance in breast cancer through SIRT1 protein stabilization. Breast Cancer Research 21: 64

 [9]Ruan Z, Sun Q, Jia H, Huang C, Zhou W, Xie X, Zhang J (2019) Emergence of a ST2570 Klebsiella pneumoniae isolate carrying mcr-1 and blaCTX-M-14 recovered from a bloodstream infection in China. Clinical Microbiology and Infection 25 (7):916-918

招生信息：临床检验诊断学博士(科学及专业），硕士(科学及专业）；医学遗传学博士、硕士